switchSENSE®
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Bifunctional biosensors for the analysis of bispecific antibodies I Presentation
Bispecific Challenges?
switchSENSE® Bifunctional Biosensors are the solution.
Learn more about the advantages of switchSENSE® technology:
- Straightforward sensor functionalization with two different antigens
- Variable ligand density to control interlinking when multivalent binders are measured
- Easily adjustable antigen surface ratio to mimic cell surface abundances
- Dual-color technology to monitor each interaction individually
- Stable signals for long dissociations to measure slow avidity off-rates
- switchANALYSIS software with bi-phasic fitting algorithms to discern affinity and avidity
- switchSENSE® size analysis to assess antigen stability on the sensor surface