Publication | Dynamic Biosensors

Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE

Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE I Paper Function, activity, and interactions of proteins crucially depend on their three-dimensional structure and are often regulated by effector binding and...

The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies

The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies I Paper The cytokine tumor necrosis factor-alpha (TNF-α) readily forms homotrimers at sub-nM concentrations to promote...

An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2

An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2 I Paper The recognition of cis-regulatory RNA motifs in human transcripts by RNA binding proteins (RBPs) is essential for gene regulation. The molecular...

Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics

Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics I Paper Oligonucleotide-conjugated antibodies have gained importance for their use in protein diagnostics. The possibility to transfer the readout...

Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology

Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology I Paper We have discovered the sirtuin‐rearranging ligands (SirReals) to be highly potent and selective inhibitors of...

« Older Entries

Nucleotide binding kinetics and conformational change analysis of tissue transglutaminase with switchSENSE

The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies

An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2

Preparation of single- and double-oligonucleotide antibody conjugates and their application for protein analytics

Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology

CONTACT US! WE WILL GET IN TOUCH WITH YOU SHORTLY.

CONTACT US!
WE WILL GET IN TOUCH WITH YOU SHORTLY.