Small Molecules | Dynamic Biosensors

Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology

Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology I Paper We have discovered the sirtuin‐rearranging ligands (SirReals) to be highly potent and selective inhibitors of...

switchSENSE® – Biophysical Analysis with Electro-Switchable Biosurfaces

switchSENSE®ApplicationLibrary switchSENSE® – Biophysical Analysis with Electro-Switchable Biosurfaces I Presentation Join us for this recorded webinar presentation to learn more about dynamicBIOSENSORS’ pioneering switchSENSE® sensor platform: an...

Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus

switchSENSE®ApplicationLibrary Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus I Publication Celastrol is a natural pentacyclic triterpene used in traditional Chinese medicine...

Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues

switchSENSE®ApplicationLibrary Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues I Paper A combined structural and quantitative biophysical profile of the DNA binding affinity, kinetics and...

switchSENSE® Protein Size. Different Size = Different Switching Speed

switchSENSE®ApplicationLibrary switchSENSE® Protein size = Different size = Different switching speed I...

Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology

switchSENSE® – Biophysical Analysis with Electro-Switchable Biosurfaces

Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus

Structural and Kinetic Profiling of Allosteric Modulation of Duplex DNA Induced by DNA-Binding Polyamide Analogues

switchSENSE® Protein Size. Different Size = Different Switching Speed

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